The research interests in the Luo Laboratory are immunological and microbial regulation of autoimmunity and immunodeficiency. On the immunological side, we are interested in the roles of dendritic cells in inflammation; while on the microbial side, we focus on how commensal bacteria in the gut affect the host immune system, and vice versa. We utilize murine models and human patient samples to study various diseases including systemic lupus erythematosus and primary immunodeficiencies.