Expertise includes general internal medicine and a special interest in clinincal neurology. Research interests are also in the area of inflammation/endotoxemia and in the diagnosis and biology of equine protozoal myeloencephalitis (EPM). Through this work, the pathogenesis of endoxemia in horses has been clarified and at least one new treatment developed and extensively used. In the field if EPM, Dr. MacKay has contributed to an understanding of the life cycle of the parasite and is actively involved in developing new and more satisfactory diagnostic tests.