Development of a time and cost-effective platform to screen lineage B betacoronaviruses for their ability to use different host receptors and infect human and other mammalian-derived cell lines
Screened the host-receptor preferences for the majority of currently-known lineage B betacoronaviruses showing that several viruses in this group, found circulating in bats, are capable of infecting human cells
Used to effectively demonstrate, in the laboratory, the host-r eceptor for SARS-CoV-2, in under 12 days from the release of the first viral genome.
