Dr. Sethi's main research focus is on airway hyper-responsiveness and lung inflammation. The ongoing and past research has been directed on pulmonary immune modulations following exposure to various environmental pollutants specially pesticides and characterization of single cell transcriptome(s) and proteomes of immune cells during host pathogen interplay. He has published more than 100 original research articles in scientific journals, 110 abstracts and presented more than 20 invited talks.